Friday, April 25, 2008

Nature Clinical Practice Nephrology | C-reactive protein is neither a marker nor a mediator of atherosclerosis


I just came across this interesting article in Nature Clinical Practice Nephrology explaining why CRP should be considered neither a marker nor a mediator of atherosclerosis.
Below is the abstract and link to the article (requires paid subscription)


Nature Clinical Practice Nephrology | C-reactive protein is neither a marker nor a mediator of atherosclerosis

Viewpoint

Nature Clinical Practice Nephrology (2008) 4, 234-235
doi:10.1038/ncpneph0778  
Received 26 November 2007 | Accepted 11 January 2008 | Published online: 4 March 2008

C-reactive protein is neither a marker nor a mediator of atherosclerosis

Mark B Pepys

Correspondence Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, Royal Free Campus, University College London, Rowland Hill Street, London NW3 2PF, UK

Email
 m.pepys@medsch.ucl.ac.uk

It is widely asserted that C-reactive protein (CRP) is a strong independent predictor of atherothrombotic events, and furthermore that CRP is also a pathogenic mediator of atherosclerosis. Here, the author, who first reported the predictive association of CRP with atherothrombotic events, attempts to correct these misapprehensions. He highlights the lack of a convincing association between CRP values and atherosclerosis burden, the fact that the association between baseline CRP values and coronary heart disease is substantially weaker than originally claimed, the nonspecificity of the CRP response and the flaws of cell culture studies with recombinant CRP.

Friday, August 10, 2007

The Daily Star - Politics - Research shows Lebanon's coast in danger of being devastated by tsunami - Sent Using Google Toolbar

The Daily Star - Politics - Research shows Lebanon's coast in danger of being devastated by tsunami

Research shows Lebanon's coast in danger of being devastated by tsunami

Daily Star staff
Friday, August 10, 2007


BEIRUT: A new underwater survey has revealed that Lebanon lies dangerously close to a fault that could soon generate a catastrophic tsunami, according to a report by Discovery News channel. The fault, which according to the survey lies just four miles off Lebanon's coast, caused a tsunami-generating earthquake in 551 A.D. that devastated the coastal cities of Phonecia, or modern-day Lebanon.

The underwater survey was carried out by a team of international geophysicists, Discovery wrote in an article published on Thursday.

The previously unknown submarine fault is responsible for the build-up of the Mount Lebanon range that towers around 10,000 meters above sea level, Discovery said.

The fault moves approximately every 1,500 years, meaning that a disaster of the same magnitude as the earthquake and tsunami that destroyed coastal cities on July 9, 551, could be due any day.

According to historical accounts, that ancient event caused the sea to retreat up to 10,000 meters, Discovery said.

Tripoli was reported to have "drowned," while Beirut took nearly 1,300 years to recover from the cataclysm.

"It was arguably one of the most devastating historical submarine earthquakes in the eastern Mediterranean," Ata Elias of the National Center for Geophysical Research in Beirut, Lebanon, and colleagues wrote in the current issue of the journal Geology.

To trace the origin of the disaster, Elias and colleagues used high-resolution sonar to map the contours of the sea floor between the Lebanese coastal towns of Enfeh and Damour.

"The images show details of spectacular submarine ruptures ... that cut the smoothly sediment-mantled seafloor," the researchers wrote.
http://www.dailystar.com.lb


Along the coast offshore of Mount Lebanon, the team of researchers found relatively fresh seafloor seismic breaks, indicating that an active thrust fault is responsible for major earthquakes there.

Based on their research, the team estimated that the 551 disaster was caused by a rupture at least 62 miles long on the offshore Mount Lebanon thrust.

The rupture caused a magnitude 7.5 quake. Part of the seafloor collapsed by 5 to 10 feet, triggering a tsunami.

Their research also revealed that at least four earthquakes similar to the 551 event have occurred over the past 6,000 to 7,000 years, suggesting that the seismic behavior of the Mount Lebanon thrust is characterized by a series of clustered quakes separated by 1,500 to 1,750 years of relative calm.

If so, the quakes in 1837, 1918 and 1956 "might be forerunners of worse to come," the researchers concluded.

According to Rob Butler of University of Leeds's Institute of Geophysics and Tectonics, the researchers "make a convincing case about the source of the A.D. 551 earthquake."

But he is not convinced that earthquakes of the last few decades might be harbingers of the next "big one."

"There is an unavoidable certainty that the [area] will be struck by a devastating earthquake. But it could be any time, perhaps within the next few years, perhaps a hundred years from now," he told Discovery.

"The bottom line is, we don't know the odds. In the case of Lebanon, people are literally betting their lives and houses on it," he added. - The Daily Star

Wednesday, August 08, 2007

The Daily Star - Business Articles - Lebanon telecom authority promises solution to DSL woes - Sent Using Google Toolbar

The Daily Star - Business Articles - Lebanon telecom authority promises solution to DSL woes

Lebanon telecom authority promises solution to DSL woes

Daily Star staff
Wednesday, August 08, 2007

Lebanon telecom authority promises solution to DSL woes

BEIRUT: The head of the Telecom Regulatory Authority (TRA) Kamal Shehadi said on Tuesday that all problems facing the DSL Internet connection will be resolved once the highly anticipated LibanTelecom company is set up. Shehadi gave these assurances during a meeting between Ogero officials and representatives of the Internet service providers (ISPs) in Lebanon.

The ISPs complain that Ogero is not supplying them with sufficient bandwidth and international gateways to meet the growing demand for the popular DSL service.

Lebanon introduced DSL more than three months ago, however, most areas in the country still do not have access to the service.

According to well-informed sources, the number of DSL subscribers in the country is still less than 4,000. The ISPs are also furious because of the 4,000 DSL subscribers, most are actually Ogero clients.

Shehadi, who was appointed as head of the TRA more than seven months ago in an attempt to speed up the privatization of the telecom industry, promised to oversee the spread of DSL to most areas as soon as possible.

But he told the representatives that the telecom sector needs to be liberalized to better serve all customers.

"The DSL problems are mainly due to the absence of LibanTelecom in addition to the nature of the current laws," the head of the TRA said.
http://www.dailystar.com.lb


He added that there should be no discrimination and favoritism in the field of telecommunication and DSL.

"The DSL should be spread to all areas so that all Lebanese will be able to use this service," Shehadi said.

He added that both Ogero and the ISPs should launch a joint media campaign to enlighten the consumers and specify the next areas that will benefit from the DSL.

Some critics have said that the government-owned Ogero should not compete with the ISPs in the field of Internet, adding that the private sector should have the sole right to install and sell Internet services in Lebanon.

Some of the ISPs say that the government is selling the bandwidth at exorbitant prices which hinders their efforts to provide good quality Internet service to the end user.

"The prices of the bandwidth in Lebanon are three times higher than Europe and the rest of the world. The government should allow the ISPs to buy the bandwidth directly from abroad," one Internet provider said.

He added that Ogero is taking advantage of its large size in Lebanon to sell and install the DSL much quicker than the rest of the private companies. - The Daily Star

Saturday, August 04, 2007

The Lancet Student: Leading the way in global health




The Lancet, one of the world's leading general medical journals, has launched a new website exclusively for medical students worldwide.

Many students may already be familiar with www.thelancet.com, the main online portal for The Lancet family of journals, which has attracted 1.6 million registered users since its launch in 1996.

But TheLancetStudent.com is going to be something rather different, according to David Allen of The Lancet. "All content on the new site is selected for its relevance and interest to a student audience. In fact, much of it will be written by students themselves."

The Lancet is well known for its leadership role in bringing pressing global health needs and issues of health inequality to a wider audience. These are issues of increasing interest to the world's medical students as so many more of them now opt for overseas electives, often in the developing world. So global health issues will take centre stage on the new site. Rhona MacDonald, The Lancet editor charged with overseeing TheLancetStudent.com (she's also a former editor of the Student BMJ!) tells us:

" TheLancetStudent.com will be a great place for students themselves to write about global health issues and other international medical areas. We hope they will submit reports on their own electives to us so that these can be shared with medical students worldwide. Users will also be able to read a free weekly summary of The Lancet's content, comment on the daily blog and access many of the global health resources of the main Lancet site.

She added "There will also be weekly online polls - and the opportunity to test your clinical knowledge with Crash Course Quizzes."

Please visit TheLancetStudent.com and let them know what you think of the site and what you want from it. The Lancet team tell us: " TheLancetStudent.com is YOUR site and we want to shape and develop it with your help."

- Write about global health issues and other international medical areas

- Read a free weekly summary of The Lancet's content

- Comment on the daily blog

- Take part in online polls and Crash Course Quizzes

- Use the global health resources of The Lancet


You are receiving this e-mail because you are a registered user of the FleshandBones website. If you would prefer not to receive any further emails from THE LANCET, please send an email to: david.allen@lancet.com with the subject line 'UNSUBSCRIBE.' Please allow 5 working days for us to process your request. Please do not reply to this e-mail as it is post-only and cannot be read.


--
Georges Azzi
http://azzi.org
Beirut,Lebanon

Sunday, June 03, 2007

Link to call me for free

I am using jaxtr, and if you also sign up, we can talk for free on the phone at any time.

-Georges

P.S. Here is the link to sign up:
http://www.jaxtr.com/user/ticket?n=T122h3uq&type=joininvite

Tuesday, May 15, 2007

The Daily Star - - Beirut introduces affordable high-speed Internet - Sent Using Google Toolbar

The Daily Star - - Beirut introduces affordable high-speed Internet

Beirut introduces affordable high-speed Internet


By Michael Bluhm
Daily Star staff

 

BEIRUT: High-speed ADSL Internet officially arrived in Lebanon Monday, as Premier Fouad Siniora and Telecommunications Minister Marwan Hamadeh welcomed the most populous areas into the ADSL network. Monday's ceremony was largely symbolic, as one week ago the country's Internet service providers (ISPs) tapped into the new lines installed by monopoly telecom operator Ogero. So far, the service covers 10 telecom districts, known as central offices: Riad al-Solh, Achrafieh, Karantina, Ras Beirut, Mina al-Hosn, Bir Hassan, Jounieh, Zahle, Sidon and Mina in Tripoli.

Customers in these areas who order now will have to wait one to two weeks for installation of the service, which uses existing analog phone lines to establish an uninterrupted connection while still allowing for simultaneous phone conversations.

The service has rolled out at prices rivaling those for unpredictable dial-up connections, and ISPs reported brisk demand for ADSL since they started accepting applications last week.

The ado accompanying ADSL stems not only from its competitive pricing, but also because many countries have seen their economies goosed by the multiplier effect of providing widespread access to high-speed Internet.

"Lebanon was outside the knowledge economy, and now it enters it through the front door," said Hamadeh.

The dynamics of ADSL in Lebanon also have to take into account rampant piracy, as roughly 30 percent of all Internet connections go through illegal satellite providers. To fight piracy and reap the economic benefits associated with ADSL, all parties' concerned stress the key factor will be how quickly ADSL can be made available to as many people as possible.

"The most important thing is how fast we deploy," said the provider's executive director, Maroun Chammas. "I'm sure it's going to help the economy."

The next round of central offices, slated for connection in mid-June, includes Mazraa, Ras al-Nabeh, Zouk, Antelias, Jal al Dib, Mazraat Yachouh, Qornet Shehwan, Broummana, Mansourieh, Dbayyeh, Badaro, Adlieh and Jdeideh. Twelve more central offices have been tabbed for ADSL this year: Tripoli Tell, Dora, Sin al-Fil, Hazmieh, Dekwaneh, Mreijeh, Amrousieh, Elissar, Aley, Choueifat, Damour and Shiyah. Next should witness about 60 more central offices, such as Baalbek, the Bekaa and the rest of the South picking up the service, which would mean 90 percent of the nation's active phone lines would have access to ADSL connections.

To hasten the spread of the product, ISPs have been pressuring Ogero to increase its capacity to connect new clients. Ogero has promised to hook up 50 customers per day, while Hamadeh told The Daily Star he will take the steps to meet the ministry's goal of 45,000 connections this year. Looking over the ministry's shoulder will be the recently established Telecommunications Regulatory Authority (TRA), which has issued its input on how it expects the rollout to proceed.

"For this service to be launched on a sustainable basis a lot more needs to be done," said TRA Chairman Kamal Shehadi. "This is just the beginning of a long process before we can say we have nationwide ADSL coverage."

ISPs and Ogero are offering ADSL for an installation charge of $38 and monthly fees based on connection speed: 128 kilobits per second (kbps) at $23.90, 256 kbps at $33.90, 512 kbps at $46.90 and 1 Mbps at $76.90, with respective monthly caps of 2GB, 3GB, 4GB and 5 GB of free monthly traffic.

 

Beirut introduces affordable high-speed Internet

 
 

Sent to you by azzimd via Google Reader:

 
 

Beirut introduces affordable high-speed Internet

via The Daily Star > Lebanon Business by Michael Bluhm on May 14, 2007

High-speed ADSL Internet officially arrived in Lebanon Monday, as Premier Fouad Siniora and Telecommunications Minister Marwan Hamadeh welcomed the most populous areas into the ADSL network. Monday's ceremony was largely symbolic, as one week ago the country's Internet service providers (ISPs) tapped into the new lines.

 
 

Things you can do from here:

 
 

Wednesday, May 09, 2007

DSL details finally nnounced by OGERO LEBANON

Introduction

*
MOT/Ogero is offering the Broadband Internet over DSL service for the first time in Lebanon.

*
DSL (Digital Subscriber Line) technology is the worldwide most adopted technology to get Broadband Internet. The power of this technology comes from the fact that you can connect to the Internet over the existing telephone wires. You can browse the Internet and make phone calls at the same time.

*
Users who are already using the second telephone line for accessing Internet, simply switch to DSL line.

*
Moreover, we intend to offer you additional multimedia services over your DSL connection.

*
This service allows you to get on-line 24 hours/24 without the need for dial-up. You can also choose from a range of speeds offered by MOT/OGERO starting from 128 Kbps to 2 Mbps depending on your needs.

*
This service will now be available in the following 10 exchanges:
1. Riad El Solh
2. Mina El Hosn
3. Ras Beirut
4. Naher Beirut
5. Achrafieh
6. Bir Hassan
7. Jounieh
8. Tripoli Mina
9. Saida
10. Zahle
Later on, it will be progressively available all over Lebanon.
Download/Upload, Free Volume Usage Residential Businesses Educational institutions
128Kbps/32Kbps, 2 GB 35,000 L.L 45,000 L.L 30,000 L.L
256Kbps/64Kbps, 3 GB 50,000 L.L 65,000 L.L 40,000 L.L
512Kbps/128Kbps, 4 GB 70,000 L.L 85,000 L.L 60,000 L.L
1024Kbps/256Kbps, 5 GB 115,000 L.L 135,000 L.L 100,000 L.L
HDSL Up to 2.3Mbps/2.3Mbps, 8 GB 300,000 L.L 300,000 L.L 240,000 L.L

Note:

* Prices are subject to 10% VAT.
* If you exceed the free granted monthly volume for each speed, you'll be charged a 500 L. L for each additional 10 MB.

Friday, May 04, 2007

Minister announces Lebanon will launch DSL next week

 
 

Sent to you by azzimd via Google Reader:

 
 

Minister announces Lebanon will launch DSL next week

via The Daily Star > Lebanon Business by Michael Bluhm on May 03, 2007

The long-awaited and oft-delayed rollout of DSL high-speed Internet is set to begin next week, with Internet subscribers in the country's most-populous quarters scheduled to gain access to working DSL connections this month, according to the Telecommunications Ministry. Monopoly telecom provider Ogero will hook up.

 
 

Things you can do from here:

 
 

Wednesday, May 02, 2007

Send FREE UNLIMITED GLOBAL SMS using GOOGLE

IMPORTANT: READ THIS FIRST Detailed Instructions to SETUP FREE SMS

1. go to http:www.gmail.com
2. click on sign up
3. complete the details and sign up for your new account
4. Once you're signed into your account click on calendar in the upper left hand corner
5. sign in using the same user name and password
6. select the right country
7. Once you're signed in click on Settings---->Mobile Setup
8. In the mobile phone filed enter your number without the international code eg 03111111
9. Click on send verification code, you will receive a verification code by SMS enter it in the verification field and click on FINISH SETUP to verify your account and then click on save.
10. Click on calendars then clikc on the calendar that has your name.
11. On the calendar settings page click on notifications and then TICK ALL THE BOXES THEN CLICK SAVE
11. YOU ARE NOW READY TO SEND AND RECEIVE FREE SMS USING GOOGLE CALENDAR

HOW TO SEND YOUR FIRST FREE SMS MESSAGE

all users wanting to send and receive free sms SHOULD KNOW EACH OTHER'S GMAIL NAMES.
YOU CANNOT SEND AN SMS TO A MOBILE PHONE NUMBER DIRECTLY.

TO SEND YOUR SMS :
1. go to http://calendar.google.com
2. sign in using the gmail username and password
3.click on CREATE EVENT
4. Enter your message(up to 60 characters) in the what field, continue it in the where field(up to 30 characters)
5. Enter the other person gmail address in the guests field ( you can send the same msg to more than one person, just seperate the addresses by comas)
6. Click Save then send notification.
7. THE OTHER PERSON WILL RECEIVE THE MSG ON THEIR MOBILE PHONE